Heavy metal toxicity

Behavioral & Functional Abnormalities Associated with Heavy Metal Toxicity
Brain and Central Nervous System  
Neuro-fibrillary tangles Aluminum
Neuritis, retro-bulbar neuritis; neuropathy Aluminum, Arsenic, Thallium
Encephalopathy Aluminum, Arsenic, Lead, Thallium
Cerebro vascular disease X metals
Alterations in nerve conduction velocity Lead
Alterations in the spinal cord Thallium
Assumulates in CNS structures Aluminum, Mercury
Abnormal EEGs Arsenic, Lead
Autonomic disturbances Copper, Lead, Mercury, Thallium
Gastrointestinal Tract  
Nausea, vomiting, diarrhea; loss of appetite Arsenic, Copper, Mercury, Thallium
Abdominal pain, stomach cramps; burning of the throat and mouth Arsenic, Copper, Lead, Mercury, Thallium
Esophagitis; gastroenteritis; colitis Arsenic, Mercury, Thallium
Cancers (colon, pancreatic, stomach, or rectal) Arsenic
Peripheral Nervous System  
Peripheral neuropathy Arsenic, Mercury
Alterations in peripheral nerves Arsenic
Loss of feeling/numbness in the extremities; paresthesia Arsenic, Mercury, Thallium
Renal and Hepatic Impairment  
Hepato-toxicity; liver dysfunction, damage Arsenic, Copper, Thallium
Cirrhosis of the liver; hepatitis Copper
Kidney disease; kidney failure Arsenic, Lead, Mercury
Renal toxicity; tubular proteinosis Arsenic, Copper, Lead
Kidney damage, histological alterations Arsenic, Lead
Cardiovascular System  
Blood vessel damage Arsenic
Anemia; decreased red blood cell count Arsenic, Copper
Lead Hypertension; increased heart rate (tachycardia) Arsenic, Copper, Lead, Thallium
Peripheral vascular disease; cardiovascular disease, vascular collapse Arsenic, Lead
Respiratory System  
Pulmonary fibrosis Aluminum, Arsenic
Pulmonary endema X metals
Pneumonia, laryngitis, pharyngitis, bronchitis Aluminum, Arsenic, Mercury
Restrictive airway disorders, asthmatic conditions, pneumoconisis Arsenic, Aluminum
Respiratory tract disorders Arsenic
Nasal ulcers, perofraction of the nasal septum X metals
Immune System  
Increased incidences of asthma, autoimmune-like symptoms, & allergies X metals
Inhibition of lymphocytes, T-cells, monocytes X metals
Immuno-suppression Lead
Decreased white blood cell count Arsenic, Thallium
Reproductive System  
Genital abnormalities Aluminum, Thallium
Disturbances in menstrual cycle; menstrual pains Copper, Mercury
Birth defects; premature births; spontaneous abortion Arsenic, Lead, Mercury
Reproductive dysfunction Arsenic, Aluminum, Cadmium, Lead
Psychiatric Disturbances  
Social Deficits, Social Withdrawal Mercury
Repetitive, perseverative, stereotyped behaviors, OCD-typical behaviors Mercury
Depression, mood swings, flat affect; impaired facial recognition Arsenic, Copper, Lead, Mercury
Scizoid tendencies; hallucinations; delirium Mercury
Irritability, aggressive behaviors, temper tantrums Lead, Mercury
Suicidal behavior Copper, Mercury
Sleep difficulties/disturbances Lead, Mercury, Thallium
Chronic Fatigue Syndrome (CFS); weakness, malaise Aluminum, Arsenic, Cadmium, Copper, Lead, Mercury, Thallium
Anorexia; symptoms reflecting eating disorders, loss of appetite/weight Arsenic, Lead, Mercury
Anxiety; nervous tendencies Thallium
Attention problems (ADHD), lacks eye contact, impaired visual fixation Lead, Mercury
Speech and Language Deficits  
Speech Disorders Aluminum, Mercury
Loss of Speech, developmental problems with language Mercury
Speech comprehension deficits Mercury
Dysarthria; articulation problems; slurred speech, unintelligible speech Mercury
Cognitive Impairments  
Mental retardation, borderline intelligence Arsenic, Lead, Mercury
Uneven performance on IQ scores, low IQ scores Copper, Lead
Poor concentration, attention deficits (ADHD), response inhibition Aluminum, Lead
Poor memory (short term, verbal and auditory) Aluminum, Lead
Difficulties understanding abstract ideas; difficulty carrying out complex commands X metals
Dementia; pre-senile and senile dementia Aluminum
Stupor Aluminum
Impaired reaction time; lower performance on timed tests Lead
Sensory Abnormalities  
Abnormal sensations in the mouth and extremities Arsenic
Hearing loss, difficulty hearing Arsenic, Lead, Mercury
Abnormal touch sensations; diminished touch sensations, aversion to touch Arsenic
Blurred vision, sensitivity to light Arsenic, Mercury
Motor Disorders  
Choreiform movements, myoclonal jerks, unusual postures Copper, Mercury
Difficulty walking, swallowing, talking, flapping, circuling, rocking, toe walking Copper, Mercury
Problems with intentional movements or imitation Mercury
Abnormal gait/posture; in co-ordination, loss of balance; problems sitting, lying, crawling, and walking Mercury
Decreased loco-motor activity Aluminum, Arsenic
Convulsions; seizure Aluminum, Arsenic, Copper, Lead, Mercury, Thallium
Other Physical Disturbances  
Hypotonia or hypertonia; decreased muscular strength X metals
Rashes, contact dermatitis, eczema, itchy/irritating skin Arsenic, Copper, Lead, Mercury
Muscle pain; headache; acrodynia; colic Arsenic, Copper, Lead, Thallium
Alopecia (hair loss) Thallium